Epilepsy as a Window to Mechanisms of Neuronal Plasticity

The EpiCenter offers a 4 unit graduate-postgraduate course on basic mechanisms of epilepsy every other year. The course provides new insights into the normal function of neurons and circuits, and it covers a wide range of epilepsy-related topics, from basic molecular/epigenetic/cellular questions to translational research and clinical aspects.

Course code: 90330 Winter 2023

Day/Time: Friday 4:00 PM – 5:00 PM (unless otherwise noted)

Location: https://uci.zoom.us/j/98508590118?pwd=dm5vVzVhYkxmam9RUlBGZzNEa0Yydz09

Meeting ID: 985 0859 0118

Passcode: 712663

Logistics & Changes Organizer: Brittney Boublil, PhD (bboublil@hs.uci.edu)

2023 Course Schedule

Topic	Speaker	Date/Time
Foundations of Epilepsy: How does the brain become epileptic?	Tallie Z. Baram, MD, PhD Prof., Pediatrics, Anatomy & Neurobiology, Neurology, Physiology & Biophysics	Jan 13 4 p.m.
Medical treatment of epilepsy; Epilepsy in women	Mona Sazgar, MD, FAES Prof., Clinical Neurology Director, UCI Comprehensive Epilepsy Program Chair of Diversity (IDEAS) Committee Department of Neurology, UC Irvine Health	Jan 20 3 p.m.
Epilepsy Surgery: Past, Present, Future	Sumeet Vadera, MD Neurological Surgery, UC Irvine Health	Jan 27 4 p.m.
Sparse to dense networks: impacts on pattern separation and pattern completion	Laura A. Ewell, PhD Assist. Prof., Anatomy & Neurobiology	Feb 3 4 p.m.
New molecules and processes in epilepsy and its cognitive co-morbidities	Lulu Y. Chen, PhD Assist. Prof., Anatomy & Neurobiology	Feb 10 4 p.m.
Seizure effects on gene expression provide insight into forms of activity-induced plasticity across a broad spectrum	Christine M. Gall, PhD Prof., Neurobiology & Behavior, Anatomy & Neurobiology Chair, Anatomy & Neurobiology	Feb 17 3 p.m.
Mechanisms of AMPA receptor trafficking, synaptic plasticity and epilepsy	Javier Diaz Alonso, PhD Assist. Prof., Anatomy & Neurobiology	Feb 24 4 p.m.
Cell-type specific alteration in hippocampal dentate interneuronal circuits in acquired epilepsy	Viji Santhakumar, PhD Prof., Molecular Cell & Systems Biology, UCR Vice Chair, Molecular Cell & Systems Biology, UCR	Mar 3 4 p.m.
Ligand activation of neuronal voltage-gated potassium channels	Geoffrey W. Abbott, PhD Prof., Physiology & Biophysics, School of Medicine Senior Assoc. Dean, Academic Personnel Vice Dean, Basic Science Research	Mar 10 4 p.m.
Thinking about therapy	Robert Hunt, PhD Assoc. Prof., Anatomy & Neurobiology Director, Epilepsy Research Center	Mar 17 3 p.m.
Final exam		Mar 24