New options in the fight against epilepsy
At the EpiCenter, we are developing new breakthrough therapies for epilepsy and related brain conditions — and those breakthroughs start in the lab.
Our team of investigators are laser-focused on uncovering the basic biology of epilepsy and using this information to develop new therapies. Powered by a modular discovery platform that is flexible and efficient, promising pre-clinical lead candidates are emerging from our laboratories, and we continue to innovate in the areas of drug discovery and repurposing, gene and cell therapy and integrative health.
our discovery platform
designed for flexibility
Our modular discovery platform leverages expertise from all areas of neuroscience and is designed to efficiently translate breakthrough discoveries into new therapies.
identify new disease targets
Uncover new mechanisms for targeting epilepsy at its source.
create precision therapeutics
Custom therapeutic technologies are designed for a specific form of epilepsy.
test our products
We have broad pre-clinical and clinical-translational capabilities at UCI and within the EpiCenter network.
partner for commercialization
We are building commercial, industry and patient community partnerships to deliver new therapies to those who need them.
A promising pipeline
Our discovery pipeline includes new compounds, gene and cell therapies and natural remedies with
promising antiseizure potential in rigorous pre-clinical epilepsy studies.
Current focus areas
Drug discovery
We are creating more effective medications to regulate the electrical activity in brain and heart and discovering new ways to repurpose existing drugs for treating epilepsy.
Cell therapy
We have played a pioneering role in developing a medial ganglionic eminence (MGE) cell therapy for intractable epilepsies, based on the transplantation of inhibitory interneurons to restore inhibition and stop seizures.
Gene therapy
We are exploring the possibility that specific genes can be delivered to the brain with high precision, influence nerve function and reduce seizures.